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Transcription-coupled DNA supercoiling in defined protein systems and in E. coli topA mutant strains
Transcription by RNA polymerases can stimulate (−) DNA supercoiling both in vitro and in E. coli topA strains. This phenomenon has been successfully explained by a "twin-supercoiled-domain" model of transcription in which (+) supercoils are produced in front of the transcribing RNA polymer...
Gorde:
| Argitaratua izan da: | IUBMB Life |
|---|---|
| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5992920/ https://ncbi.nlm.nih.gov/pubmed/23757201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.1179 |
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