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Inhibition of the gyrA promoter by transcription-coupled DNA supercoiling in Escherichia coli

The E. coli gyrA promoter (P(gyrA)) is a DNA supercoiling sensitive promoter, stimulated by relaxation of DNA templates, and inhibited by (−) DNA supercoiling in bacteria. However, whether P(gyrA) can be inhibited by transient and localized transcription-coupled DNA supercoiling (TCDS) has not been...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dages, Samantha, Dages, Kelley, Zhi, Xiaoduo, Leng, Fenfei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170449/
https://ncbi.nlm.nih.gov/pubmed/30282997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33089-4
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