載入...

Repair of Alkylation Damage in Eukaryotic Chromatin Depends on Searching Ability of Alkyladenine DNA Glycosylase

Human alkyladenine DNA glycosylase (AAG) initiates the base excision repair pathway by excising alkylated and deaminated purine lesions. In vitro biochemical experiments demonstrate that AAG uses facilitated diffusion to efficiently search DNA to find rare sites of damage, and suggest that electrost...

全面介紹

Na minha lista:
書目詳細資料
發表在:ACS Chem Biol
Main Authors: Zhang, Yaru, O’Brien, Patrick J.
格式: Artigo
語言:Inglês
出版: 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724868/
https://ncbi.nlm.nih.gov/pubmed/26317160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00409
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!