Functional screen identifies kinases driving prostate cancer visceral and bone metastasis

Mutationally activated kinases play an important role in the progression and metastasis of many cancers. Despite numerous oncogenic alterations implicated in metastatic prostate cancer, mutations of kinases are rare. Several lines of evidence suggest that nonmutated kinases and their pathways are in...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Faltermeier, Claire M., Drake, Justin M., Clark, Peter M., Smith, Bryan A., Zong, Yang, Volpe, Carmen, Mathis, Colleen, Morrissey, Colm, Castor, Brandon, Huang, Jiaoti, Witte, Owen N.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720329/
https://ncbi.nlm.nih.gov/pubmed/26621741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521674112
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