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Functional screen identifies kinases driving prostate cancer visceral and bone metastasis

Mutationally activated kinases play an important role in the progression and metastasis of many cancers. Despite numerous oncogenic alterations implicated in metastatic prostate cancer, mutations of kinases are rare. Several lines of evidence suggest that nonmutated kinases and their pathways are in...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Proc Natl Acad Sci U S A
Main Authors: Faltermeier, Claire M., Drake, Justin M., Clark, Peter M., Smith, Bryan A., Zong, Yang, Volpe, Carmen, Mathis, Colleen, Morrissey, Colm, Castor, Brandon, Huang, Jiaoti, Witte, Owen N.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720329/
https://ncbi.nlm.nih.gov/pubmed/26621741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521674112
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