Functional screen identifies kinases driving prostate cancer visceral and bone metastasis

Mutationally activated kinases play an important role in the progression and metastasis of many cancers. Despite numerous oncogenic alterations implicated in metastatic prostate cancer, mutations of kinases are rare. Several lines of evidence suggest that nonmutated kinases and their pathways are in...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Faltermeier, Claire M., Drake, Justin M., Clark, Peter M., Smith, Bryan A., Zong, Yang, Volpe, Carmen, Mathis, Colleen, Morrissey, Colm, Castor, Brandon, Huang, Jiaoti, Witte, Owen N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720329/
https://ncbi.nlm.nih.gov/pubmed/26621741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521674112
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