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A basal stem cell signature identifies aggressive prostate cancer phenotypes

Evidence from numerous cancers suggests that increased aggressiveness is accompanied by up-regulation of signaling pathways and acquisition of properties common to stem cells. It is unclear if different subtypes of late-stage cancer vary in stemness properties and whether or not these subtypes are t...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Smith, Bryan A., Sokolov, Artem, Uzunangelov, Vladislav, Baertsch, Robert, Newton, Yulia, Graim, Kiley, Mathis, Colleen, Cheng, Donghui, Stuart, Joshua M., Witte, Owen N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664352/
https://ncbi.nlm.nih.gov/pubmed/26460041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1518007112
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