N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells

MYCN amplification and overexpression are common in neuroendocrine prostate cancer (NEPC). However, the impact of aberrant N-Myc expression in prostate tumorigenesis and the cellular origin of NEPC have not been established. We define N-Myc and activated AKT1 as oncogenic components sufficient to tr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Lee, John K., Phillips, John W., Smith, Bryan A., Park, Jung Wook, Stoyanova, Tanya, McCaffrey, Erin F., Baertsch, Robert, Sokolov, Artem, Meyerowitz, Justin G., Mathis, Colleen, Cheng, Donghui, Stuart, Joshua M., Shokat, Kevan M., Gustafson, W. Clay, Huang, Jiaoti, Witte, Owen N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829466/
https://ncbi.nlm.nih.gov/pubmed/27050099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.03.001
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados