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Dual-Inhibitors of N-Myc and AURKA as Potential Therapy for Neuroendocrine Prostate Cancer

Resistance to androgen-receptor (AR) directed therapies is, among other factors, associated with Myc transcription factors that are involved in development and progression of many cancers. Overexpression of N-Myc protein in prostate cancer (PCa) leads to its transformation to advanced neuroendocrine...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Ton, Anh-Tien, Singh, Kriti, Morin, Hélène, Ban, Fuqiang, Leblanc, Eric, Lee, Joseph, Lallous, Nada, Cherkasov, Artem
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7663809/
https://ncbi.nlm.nih.gov/pubmed/33167327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218277
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