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Development of Novel Inhibitors Targeting the D-Box of the DNA Binding Domain of Androgen Receptor
The inhibition of the androgen receptor (AR) is an established strategy in prostate cancer (PCa) treatment until drug resistance develops either through mutations in the ligand-binding domain (LBD) portion of the receptor or its deletion. We previously identified a druggable pocket on the DNA bindin...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7958344/ https://ncbi.nlm.nih.gov/pubmed/33801338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052493 |
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