Development of an Androgen Receptor Inhibitor Targeting the N-Terminal Domain of Androgen Receptor for Treatment of Castration Resistant Prostate Cancer

SIMPLE SUMMARY: In almost all patients, the proliferation and growth of prostate cancer is driven by the androgen receptor. Given this critical role, inhibiting the androgen receptor is the standard of care following surgery or radiotherapy. However, the effectiveness of current anti-androgen therap...

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Published in:Cancers (Basel)
Main Authors: Ban, Fuqiang, Leblanc, Eric, Cavga, Ayse Derya, Huang, Chia-Chi Flora, Flory, Mark R., Zhang, Fan, Chang, Matthew E. K., Morin, Hélène, Lallous, Nada, Singh, Kriti, Gleave, Martin E., Mohammed, Hisham, Rennie, Paul S., Lack, Nathan A., Cherkasov, Artem
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304761/
https://ncbi.nlm.nih.gov/pubmed/34298700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143488
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