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Structure of mammalian eIF3 in the context of the 43S preinitiation complex
During eukaryotic translation initiation, 43S complexes, comprising a 40S ribosomal subunit, initiator tRNA and initiation factors (eIF) 2, 3, 1 and 1A, attach to the 5’-terminal region of mRNA and scan along it to the initiation codon. Scanning on structured mRNAs additionally requires the DExH-box...
Enregistré dans:
| Publié dans: | Nature |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4719162/ https://ncbi.nlm.nih.gov/pubmed/26344199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14891 |
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