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Roles of individual domains in the function of DHX29, an essential factor required for translation of structured mammalian mRNAs

On most eukaryotic mRNAs, initiation codon selection involves base-by-base inspection of 5′ UTRs by scanning ribosomal complexes. Although the eukaryotic initiation factors 4A/4B/4G can mediate scanning through medium-stability hairpins, scanning through more stable structures additionally requires...

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Detalhes bibliográficos
Main Authors: Dhote, Vidya, Sweeney, Trevor R., Kim, Natalia, Hellen, Christopher U. T., Pestova, Tatyana V.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503174/
https://ncbi.nlm.nih.gov/pubmed/23047696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208014109
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