Toward the mechanism of eIF4F-mediated ribosomal attachment to mammalian capped mRNAs

Ribosomal attachment to mammalian capped mRNAs is achieved through the cap–eukaryotic initiation factor 4E (eIF4E)–eIF4G–eIF3–40S chain of interactions, but the mechanism by which mRNA enters the mRNA-binding channel of the 40S subunit remains unknown. To investigate this process, we recapitulated i...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Genes Dev
Asıl Yazarlar: Kumar, Parimal, Hellen, Christopher U.T., Pestova, Tatyana V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949329/
https://ncbi.nlm.nih.gov/pubmed/27401559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.282418.116
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