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Structure of the mammalian ribosomal 43S preinitiation complex bound to the scanning factor DHX29
Eukaryotic translation initiation begins with assembly of a 43S preinitiation complex. First, Met-tRNA(i)(Met), eukaryotic initiation factor 2 (eIF2) and GTP form a ternary complex (TC). The TC, eIF3, eIF1 and eIF1A cooperatively bind to the 40S subunit yielding the 43S preinitiation complex, which...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3730827/ https://ncbi.nlm.nih.gov/pubmed/23706745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.04.036 |
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