Structure of the mammalian ribosomal pre-termination complex associated with eRF1•eRF3•GDPNP

Eukaryotic translation termination results from the complex functional interplay between two release factors, eRF1 and eRF3, in which GTP hydrolysis by eRF3 couples codon recognition with peptidyl-tRNA hydrolysis by eRF1. Here, we present a cryo-electron microscopy structure of pre-termination compl...

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Päätekijät: des Georges, Amédée, Hashem, Yaser, Unbehaun, Anett, Grassucci, Robert A., Taylor, Derek, Hellen, Christopher U. T., Pestova, Tatyana V., Frank, Joachim
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2014
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950680/
https://ncbi.nlm.nih.gov/pubmed/24335085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1279
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