Cryo-EM structure of the mammalian eukaryotic release factor eRF1–eRF3-associated termination complex

Eukaryotic translation termination results from the complex functional interplay between two eukaryotic release factors, eRF1 and eRF3, and the ribosome, in which GTP hydrolysis by eRF3 couples codon recognition with peptidyl-tRNA hydrolysis by eRF1. Here, using cryo-electron microscopy (cryo-EM) an...

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Detalhes bibliográficos
Main Authors: Taylor, Derek, Unbehaun, Anett, Li, Wen, Das, Sanchaita, Lei, Jianlin, Liao, Hstau Y., Grassucci, Robert A., Pestova, Tatyana V., Frank, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494903/
https://ncbi.nlm.nih.gov/pubmed/23091004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216730109
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