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Cryo-EM structure of the mammalian eukaryotic release factor eRF1–eRF3-associated termination complex

Eukaryotic translation termination results from the complex functional interplay between two eukaryotic release factors, eRF1 and eRF3, and the ribosome, in which GTP hydrolysis by eRF3 couples codon recognition with peptidyl-tRNA hydrolysis by eRF1. Here, using cryo-electron microscopy (cryo-EM) an...

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Main Authors: Taylor, Derek, Unbehaun, Anett, Li, Wen, Das, Sanchaita, Lei, Jianlin, Liao, Hstau Y., Grassucci, Robert A., Pestova, Tatyana V., Frank, Joachim
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494903/
https://ncbi.nlm.nih.gov/pubmed/23091004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216730109
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