Cryo-EM structure of the mammalian eukaryotic release factor eRF1–eRF3-associated termination complex

Eukaryotic translation termination results from the complex functional interplay between two eukaryotic release factors, eRF1 and eRF3, and the ribosome, in which GTP hydrolysis by eRF3 couples codon recognition with peptidyl-tRNA hydrolysis by eRF1. Here, using cryo-electron microscopy (cryo-EM) an...

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Bibliografiske detaljer
Main Authors: Taylor, Derek, Unbehaun, Anett, Li, Wen, Das, Sanchaita, Lei, Jianlin, Liao, Hstau Y., Grassucci, Robert A., Pestova, Tatyana V., Frank, Joachim
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494903/
https://ncbi.nlm.nih.gov/pubmed/23091004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216730109
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