HCV-like IRESs displace eIF3 to gain access to the 40S subunit

Hepatitis C virus (HCV) and Classical swine fever virus (CSFV) mRNAs contain related (HCV-like) internal ribosome entry sites (IRESs) that promote 5’-end independent initiation of translation, requiring only a subset of the eukaryotic initiation factors (eIFs) needed for canonical initiation on cell...

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Detalhes bibliográficos
Main Authors: Hashem, Yaser, des Georges, Amedee, Dhote, Vidya, Langlois, Robert, Liao, Hstau Y., Grassucci, Robert A., Pestova, Tatyana V., Hellen, Christopher U.T., Frank, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106463/
https://ncbi.nlm.nih.gov/pubmed/24185006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12658
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