Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants

Phenotyping of Gprc6a KO mice has shown that this promiscuous class C G protein coupled receptor is variously involved in regulation of metabolism, inflammation and endocrine function. Such effects are described as mediated by extracellular calcium, L-amino acids, the bone-derived peptide osteocalci...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rueda, Patricia, Harley, Elizabeth, Lu, Yao, Stewart, Gregory D., Fabb, Stewart, Diepenhorst, Natalie, Cremers, Béatrice, Rouillon, Marie-Hélène, Wehrle, Isabelle, Geant, Anne, Lamarche, Gwladys, Leach, Katie, Charman, William N., Christopoulos, Arthur, Summers, Roger J., Sexton, Patrick M., Langmead, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718634/
https://ncbi.nlm.nih.gov/pubmed/26785252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146846
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