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Explaining Divergent Observations Regarding Osteocalcin/GPRC6A Endocrine Signaling

A new schema proposes that the bone-derived osteocalcin (Ocn) peptide hormone activates the G-protein–coupled receptor GPRC6A to directly regulate glucose and fat metabolism in liver, muscle, and fat, and to stimulate the release of metabolism-regulating hormones, including insulin, fibroblast growt...

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Bibliografske podrobnosti
izdano v:Endocrinology
Main Authors: Pi, Min, Nishimoto, Satoru Kenneth, Darryl Quarles, L
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880225/
https://ncbi.nlm.nih.gov/pubmed/33474566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqab011
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