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Evidence for Osteocalcin Binding and Activation of GPRC6A in β-Cells
The possibility that G protein-coupled receptor family C member A (GPRC6A) is the osteocalcin (Ocn)-sensing G protein-coupled receptor that directly regulates pancreatic β-cell functions is controversial. In the current study, we found that Ocn and an Ocn-derived C-terminal hexapeptide directly acti...
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| Publicado no: | Endocrinology |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4870875/ https://ncbi.nlm.nih.gov/pubmed/27007074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-2010 |
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