Evidence for Osteocalcin Binding and Activation of GPRC6A in β-Cells

The possibility that G protein-coupled receptor family C member A (GPRC6A) is the osteocalcin (Ocn)-sensing G protein-coupled receptor that directly regulates pancreatic β-cell functions is controversial. In the current study, we found that Ocn and an Ocn-derived C-terminal hexapeptide directly acti...

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Bibliografiske detaljer
Udgivet i:Endocrinology
Main Authors: Pi, Min, Kapoor, Karan, Ye, Ruisong, Nishimoto, Satoru Kenneth, Smith, Jeremy C., Baudry, Jerome, Quarles, Leigh Darryl
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870875/
https://ncbi.nlm.nih.gov/pubmed/27007074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-2010
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