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Computationally identified novel agonists for GPRC6A.

New insights into G protein coupled receptor regulation of glucose metabolism by β-cells, skeletal muscle and liver hepatocytes identify GPRC6A as a potential therapeutic target for treating type 2 diabetes mellitus (T2D). Activating GPRC6A with a small molecule drug represents a potential paradigm-...

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Detalhes bibliográficos
Main Authors: Min Pi, Karan Kapoor, Ruisong Ye, Dong-Jin Hwang, Duane D Miller, Jeremy C Smith, Jerome Baudry, L Darryl Quarles
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2018-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC5912754?pdf=render
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