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Reduction of fibroblast size/mechanical force down‐regulates TGF‐β type II receptor: implications for human skin aging

The structural integrity of human skin is largely dependent on the quality of the dermal extracellular matrix (ECM), which is produced, organized, and maintained by dermal fibroblasts. Normally, fibroblasts attach to the ECM and thereby achieve stretched, elongated morphology. A prominent characteri...

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Bibliografische gegevens
Gepubliceerd in:Aging Cell
Hoofdauteurs: Fisher, Gary J., Shao, Yuan, He, Tianyuan, Qin, Zhaoping, Perry, Daniel, Voorhees, John J., Quan, Taihao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717276/
https://ncbi.nlm.nih.gov/pubmed/26780887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12410
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