Reduction of fibroblast size/mechanical force down‐regulates TGF‐β type II receptor: implications for human skin aging

The structural integrity of human skin is largely dependent on the quality of the dermal extracellular matrix (ECM), which is produced, organized, and maintained by dermal fibroblasts. Normally, fibroblasts attach to the ECM and thereby achieve stretched, elongated morphology. A prominent characteri...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Fisher, Gary J., Shao, Yuan, He, Tianyuan, Qin, Zhaoping, Perry, Daniel, Voorhees, John J., Quan, Taihao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717276/
https://ncbi.nlm.nih.gov/pubmed/26780887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12410
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