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YAP/TAZ regulates TGF-β/Smad3 signaling by induction of Smad7 via AP-1 in human skin dermal fibroblasts

BACKGROUND: Transcription factors YAP and TAZ function as the primary mediators of the Hippo pathway. Yet, crosstalk of YAP and TAZ with other signaling pathways remains relatively unexplored. We have explored the impact of YAP and TAZ levels on the TGF-β/Smad signaling pathway in human skin dermal...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Qin, Zhaoping, Xia, Wei, Fisher, Gary J., Voorhees, John J., Quan, Taihao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918965/
https://ncbi.nlm.nih.gov/pubmed/29695252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0232-3
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