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Smad3-dependent CCN2 mediates fibronectin expression in human skin dermal fibroblasts

The potential involvement of connective tissue growth factor (CCN2/CTGF) in extracellular matrix (ECM) production is recognized. However, the role CCN2 in fibronectin (FN) gene expression has remained incompletely understood and even controversial. Here we report that CCN2 is absolutely necessary fo...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Purohit, Trupta, Qin, Zhaoping, Quan, Chunji, Lin, Zhenhua, Quan, Taihao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340390/
https://ncbi.nlm.nih.gov/pubmed/28267785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173191
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