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Smad3-dependent CCN2 mediates fibronectin expression in human skin dermal fibroblasts

The potential involvement of connective tissue growth factor (CCN2/CTGF) in extracellular matrix (ECM) production is recognized. However, the role CCN2 in fibronectin (FN) gene expression has remained incompletely understood and even controversial. Here we report that CCN2 is absolutely necessary fo...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Purohit, Trupta, Qin, Zhaoping, Quan, Chunji, Lin, Zhenhua, Quan, Taihao
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340390/
https://ncbi.nlm.nih.gov/pubmed/28267785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173191
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