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Reduction of fibroblast size/mechanical force down‐regulates TGF‐β type II receptor: implications for human skin aging

The structural integrity of human skin is largely dependent on the quality of the dermal extracellular matrix (ECM), which is produced, organized, and maintained by dermal fibroblasts. Normally, fibroblasts attach to the ECM and thereby achieve stretched, elongated morphology. A prominent characteri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Aging Cell
Hauptverfasser: Fisher, Gary J., Shao, Yuan, He, Tianyuan, Qin, Zhaoping, Perry, Daniel, Voorhees, John J., Quan, Taihao
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717276/
https://ncbi.nlm.nih.gov/pubmed/26780887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12410
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