Reduction of fibroblast size/mechanical force down‐regulates TGF‐β type II receptor: implications for human skin aging

The structural integrity of human skin is largely dependent on the quality of the dermal extracellular matrix (ECM), which is produced, organized, and maintained by dermal fibroblasts. Normally, fibroblasts attach to the ECM and thereby achieve stretched, elongated morphology. A prominent characteri...

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Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Fisher, Gary J., Shao, Yuan, He, Tianyuan, Qin, Zhaoping, Perry, Daniel, Voorhees, John J., Quan, Taihao
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717276/
https://ncbi.nlm.nih.gov/pubmed/26780887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12410
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