Synaptic Amyloid-β Oligomers Precede p-Tau and Differentiate High Pathology Control Cases

Amyloid-β (Aβ) and hyperphosphorylated tau (p-tau) aggregates form the two discrete pathologies of Alzheimer disease (AD), and oligomeric assemblies of each protein are localized to synapses. To determine the sequence by which pathology appears in synapses, Aβ and p-tau were quantified across AD dis...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Am J Pathol
Päätekijät: Bilousova, Tina, Miller, Carol A., Poon, Wayne W., Vinters, Harry V., Corrada, Maria, Kawas, Claudia, Hayden, Eric Y., Teplow, David B., Glabe, Charles, Albay, Ricardo, Cole, Gregory M., Teng, Edmond, Gylys, Karen H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Investigative Pathology 2016
Aiheet:
Regular Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715217/
https://ncbi.nlm.nih.gov/pubmed/26718979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.09.018
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