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Extensive p‐Tau Pathology and SDS‐Stable p‐Tau Oligomers in Alzheimer's Cortical Synapses

Like amyloid beta (Aβ) oligomers, tau aggregates are increasingly recognized as potential key toxic intermediates in Alzheimer's disease (AD) and as therapeutic targets. P‐tau co‐localizes with Aβ in cortical AD synapses and may contribute to synapse dysfunction and loss. Flow cytometry analysi...

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Detaylı Bibliyografya
Asıl Yazarlar: Henkins, Kristen M., Sokolow, Sophie, Miller, Carol A., Vinters, Harry V., Poon, Wayne W., Cornwell, Lindsey B., Saing, Tommy, Gylys, Karen Hoppens
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410970/
https://ncbi.nlm.nih.gov/pubmed/22486774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2012.00598.x
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