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Extensive p‐Tau Pathology and SDS‐Stable p‐Tau Oligomers in Alzheimer's Cortical Synapses

Like amyloid beta (Aβ) oligomers, tau aggregates are increasingly recognized as potential key toxic intermediates in Alzheimer's disease (AD) and as therapeutic targets. P‐tau co‐localizes with Aβ in cortical AD synapses and may contribute to synapse dysfunction and loss. Flow cytometry analysi...

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Bibliografische gegevens
Hoofdauteurs: Henkins, Kristen M., Sokolow, Sophie, Miller, Carol A., Vinters, Harry V., Poon, Wayne W., Cornwell, Lindsey B., Saing, Tommy, Gylys, Karen Hoppens
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410970/
https://ncbi.nlm.nih.gov/pubmed/22486774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2012.00598.x
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