Extensive p‐Tau Pathology and SDS‐Stable p‐Tau Oligomers in Alzheimer's Cortical Synapses

Like amyloid beta (Aβ) oligomers, tau aggregates are increasingly recognized as potential key toxic intermediates in Alzheimer's disease (AD) and as therapeutic targets. P‐tau co‐localizes with Aβ in cortical AD synapses and may contribute to synapse dysfunction and loss. Flow cytometry analysi...

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Detalhes bibliográficos
Main Authors: Henkins, Kristen M., Sokolow, Sophie, Miller, Carol A., Vinters, Harry V., Poon, Wayne W., Cornwell, Lindsey B., Saing, Tommy, Gylys, Karen Hoppens
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410970/
https://ncbi.nlm.nih.gov/pubmed/22486774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2012.00598.x
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