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AD synapses contain abundant Aβ monomer and multiple soluble oligomers, including a 56 kDa assembly

Much evidence indicates that soluble amyloid beta (Aβ) oligomers are key mediators of early cognitive loss, but the localization and key peptide species remain unclear. We have used flow cytometry analysis to demonstrate that surviving Alzheimer's disease (AD) synapses accumulate both Aβ and p-...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sokolow, Sophie, Henkins, Kristen M., Bilousova, Tina, Miller, Carol A., Vinters, Harry V., Poon, Wayne, Cole, Gregory M., Gylys, Karen Hoppens
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193864/
https://ncbi.nlm.nih.gov/pubmed/21741125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.05.011
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