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AD synapses contain abundant Aβ monomer and multiple soluble oligomers, including a 56 kDa assembly

Much evidence indicates that soluble amyloid beta (Aβ) oligomers are key mediators of early cognitive loss, but the localization and key peptide species remain unclear. We have used flow cytometry analysis to demonstrate that surviving Alzheimer's disease (AD) synapses accumulate both Aβ and p-...

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Detalhes bibliográficos
Main Authors: Sokolow, Sophie, Henkins, Kristen M., Bilousova, Tina, Miller, Carol A., Vinters, Harry V., Poon, Wayne, Cole, Gregory M., Gylys, Karen Hoppens
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193864/
https://ncbi.nlm.nih.gov/pubmed/21741125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.05.011
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