AD synapses contain abundant Aβ monomer and multiple soluble oligomers, including a 56 kDa assembly

Much evidence indicates that soluble amyloid beta (Aβ) oligomers are key mediators of early cognitive loss, but the localization and key peptide species remain unclear. We have used flow cytometry analysis to demonstrate that surviving Alzheimer's disease (AD) synapses accumulate both Aβ and p-...

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Библиографические подробности
Главные авторы: Sokolow, Sophie, Henkins, Kristen M., Bilousova, Tina, Miller, Carol A., Vinters, Harry V., Poon, Wayne, Cole, Gregory M., Gylys, Karen Hoppens
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193864/
https://ncbi.nlm.nih.gov/pubmed/21741125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.05.011
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