Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer’s disease and apoE TR mouse cortex

The apolipoprotein E4 allele (APOE4) contributes to Alzheimer’s disease (AD) risk and APOE2 is protective, but the relevant cellular mechanisms are unknown. We have used flow cytometry analysis to measure apolipoprotein E (apoE) and amyloid beta peptide (Aβ) levels in large populations of synaptic t...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Arold, Stephen, Sullivan, Patrick, Bilousova, Tina, Teng, Edmond, Miller, Carol A., Poon, Wayne W., Vinters, Harry V., Cornwell, Lindsey B., Saing, Tommy, Cole, Gregory M., Gylys, Karen Hoppens
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404604/
https://ncbi.nlm.nih.gov/pubmed/22020632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-011-0892-1
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares