Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer’s disease and apoE TR mouse cortex

The apolipoprotein E4 allele (APOE4) contributes to Alzheimer’s disease (AD) risk and APOE2 is protective, but the relevant cellular mechanisms are unknown. We have used flow cytometry analysis to measure apolipoprotein E (apoE) and amyloid beta peptide (Aβ) levels in large populations of synaptic t...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Arold, Stephen, Sullivan, Patrick, Bilousova, Tina, Teng, Edmond, Miller, Carol A., Poon, Wayne W., Vinters, Harry V., Cornwell, Lindsey B., Saing, Tommy, Cole, Gregory M., Gylys, Karen Hoppens
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404604/
https://ncbi.nlm.nih.gov/pubmed/22020632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-011-0892-1
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items