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Deletion of Adenosine A(2A) Receptors from Astrocytes Disrupts Glutamate Homeostasis Leading to Psychomotor and Cognitive Impairment: Relevance to Schizophrenia
BACKGROUND: Adenosine A(2A) receptors (A(2A)R) modulate dopamine and glutamate signaling and thereby may influence some of the psychomotor and cognitive processes associated with schizophrenia. Because astroglial A(2A)R regulate the availability of glutamate, we hypothesized that they might play an...
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| Udgivet i: | Biol Psychiatry |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4714966/ https://ncbi.nlm.nih.gov/pubmed/25869810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.02.026 |
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