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Antagonistic Interaction between Adenosine A(2A) Receptors and Na(+)/K(+)-ATPase-α(2) Controlling Glutamate Uptake in Astrocytes
Astrocytic glutamate transporter-1 (GLT-I) is critical to control the bulk of glutamate uptake and, thus, to regulate synaptic plasticity and excitotoxicity. GLT-I glutamate uptake is driven by the sodium gradient implemented by Na(+)/K(+)-ATPases (NKAs) and the α(2) subunit of NKA (NKA-α2) is actua...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834055/ https://ncbi.nlm.nih.gov/pubmed/24259572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1828-13.2013 |
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