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Role of Na,K-ATPase α1 and α2 Isoforms in the Support of Astrocyte Glutamate Uptake

Glutamate released during neuronal activity is cleared from the synaptic space via the astrocytic glutamate/Na(+) co-transporters. This transport is driven by the transmembrane Na(+) gradient mediated by Na,K-ATPase. Astrocytes express two isoforms of the catalytic Na,K-ATPase α subunits; the ubiqui...

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Detalles Bibliográficos
Autores principales: Illarionava, Nina B., Brismar, Hjalmar, Aperia, Anita, Gunnarson, Eli
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046997/
https://ncbi.nlm.nih.gov/pubmed/24901986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098469
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