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Role of Na,K-ATPase α1 and α2 Isoforms in the Support of Astrocyte Glutamate Uptake
Glutamate released during neuronal activity is cleared from the synaptic space via the astrocytic glutamate/Na(+) co-transporters. This transport is driven by the transmembrane Na(+) gradient mediated by Na,K-ATPase. Astrocytes express two isoforms of the catalytic Na,K-ATPase α subunits; the ubiqui...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046997/ https://ncbi.nlm.nih.gov/pubmed/24901986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098469 |
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