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Local disruption of glial adenosine homeostasis in mice associates with focal electrographic seizures: a first step in epileptogenesis?

Astrogliosis and associated dysfunction of adenosine-homeostasis are pathological hallmarks of the epileptic brain and thought to contribute to seizure generation in epilepsy. We hypothesized that astrogliosis – an early component of the epileptogenic cascade – might be linked to focal seizure onset...

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Detalhes bibliográficos
Main Authors: Li, Tianfu, Lytle, Nikki, Lan, Jing-Quan, Sandau, Ursula S., Boison, Detlev
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217085/
https://ncbi.nlm.nih.gov/pubmed/21964979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21250
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