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Uncoupling of astrogliosis from epileptogenesis in adenosine kinase (ADK) transgenic mice
The astrocytic enzyme adenosine kinase (ADK) is a key negative regulator of the brain’s endogenous anticonvulsant adenosine. Astrogliosis with concomitant upregulation of ADK is part of the epileptogenic cascade and contributes to seizure generation. To molecularly dissect the respective roles of as...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3045053/ https://ncbi.nlm.nih.gov/pubmed/19674507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1740925X09990135 |
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