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Adenosine kinase is a target for the prediction and prevention of epileptogenesis in mice

Astrogliosis is a pathological hallmark of the epileptic brain. The identification of mechanisms that link astrogliosis to neuronal dysfunction in epilepsy may provide new avenues for therapeutic intervention. Here we show that astrocyte-expressed adenosine kinase (ADK), a key negative regulator of...

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Hlavní autoři: Li, Tianfu, Ren, Gaoying, Lusardi, Theresa, Wilz, Andrew, Lan, Jing Q., Iwasato, Takuji, Itohara, Shigeyoshi, Simon, Roger P., Boison, Detlev
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2157568/
https://ncbi.nlm.nih.gov/pubmed/18172552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33737
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