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Lentiviral RNAi-induced downregulation of adenosine kinase in human mesenchymal stem cell grafts: a novel perspective for seizure control

Cell therapies based on focal delivery of the inhibitory neuromodulator adenosine were previously shown to provide potent seizure suppression in animal models of epilepsy. However, hitherto used therapeutic cells were derived from rodents and thus not suitable for clinical applications. Autologous p...

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Detalhes bibliográficos
Main Authors: Ren, Gaoying, Li, Tianfu, Lan, Jiang Quan, Wilz, Andrew, Simon, Roger P., Boison, Detlev
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2205528/
https://ncbi.nlm.nih.gov/pubmed/17716659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2007.07.016
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