Mutant Disrupted-In-Schizophrenia 1 in astrocytes: focus on glutamate metabolism

Disrupted-In-Schizophrenia 1 (DISC1) is a genetic risk factor that has been implicated in major mental disorders. DISC1 binds to and stabilizes serine racemase (SR) to regulate production of D-serine by astrocytes, contributing to glutamate (GLU) neurotransmission. However, the possible involvement...

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Bibliografiske detaljer
Udgivet i:J Neurosci Res
Main Authors: Abazyan, Sofya, Yang, Eun Ju, Abazyan, Bagrat, Xia, Meng, Yang, Chunxia, Rojas, Camilo, Slusher, Barbara, Sattler, Rita, Pletnikov, Mikhail
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247786/
https://ncbi.nlm.nih.gov/pubmed/25131692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23459
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