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Mutant Disrupted-In-Schizophrenia 1 in astrocytes: focus on glutamate metabolism
Disrupted-In-Schizophrenia 1 (DISC1) is a genetic risk factor that has been implicated in major mental disorders. DISC1 binds to and stabilizes serine racemase (SR) to regulate production of D-serine by astrocytes, contributing to glutamate (GLU) neurotransmission. However, the possible involvement...
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| Publicado no: | J Neurosci Res |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4247786/ https://ncbi.nlm.nih.gov/pubmed/25131692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23459 |
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