L1 Cell Adhesion Molecule-Specific Chimeric Antigen Receptor-Redirected Human T Cells Exhibit Specific and Efficient Antitumor Activity against Human Ovarian Cancer in Mice

New therapeutic modalities are needed for ovarian cancer, the most lethal gynecologic malignancy. Recent clinical trials have demonstrated the impressive therapeutic potential of adoptive therapy using chimeric antigen receptor (CAR)-redirected T cells to target hematological cancers, and emerging s...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Hong, Hao, Brown, Christine E., Ostberg, Julie R., Priceman, Saul J., Chang, Wen-Chung, Weng, Lihong, Lin, Paul, Wakabayashi, Mark T., Jensen, Michael C., Forman, Stephen J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711972/
https://ncbi.nlm.nih.gov/pubmed/26761817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146885
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