T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia

Induction treatments for acute myeloid leukemia (AML) have remained largely unchanged for nearly 50 years, and AML remains a disease of poor prognosis. Allogeneic hematopoietic cell transplantation can achieve cures in select patients and highlights the susceptibility of AML to donor-derived immunot...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Mardiros, Armen, Dos Santos, Cedric, McDonald, Tinisha, Brown, Christine E., Wang, Xiuli, Budde, L. Elizabeth, Hoffman, Lauren, Aguilar, Brenda, Chang, Wen-Chung, Bretzlaff, William, Chang, Brenda, Jonnalagadda, Mahesh, Starr, Renate, Ostberg, Julie R., Jensen, Michael C., Bhatia, Ravi, Forman, Stephen J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2013
Témata:
Immunobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814731/
https://ncbi.nlm.nih.gov/pubmed/24030378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-12-474056
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky