T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia

Induction treatments for acute myeloid leukemia (AML) have remained largely unchanged for nearly 50 years, and AML remains a disease of poor prognosis. Allogeneic hematopoietic cell transplantation can achieve cures in select patients and highlights the susceptibility of AML to donor-derived immunot...

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Главные авторы: Mardiros, Armen, Dos Santos, Cedric, McDonald, Tinisha, Brown, Christine E., Wang, Xiuli, Budde, L. Elizabeth, Hoffman, Lauren, Aguilar, Brenda, Chang, Wen-Chung, Bretzlaff, William, Chang, Brenda, Jonnalagadda, Mahesh, Starr, Renate, Ostberg, Julie R., Jensen, Michael C., Bhatia, Ravi, Forman, Stephen J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2013
Предметы:
Immunobiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814731/
https://ncbi.nlm.nih.gov/pubmed/24030378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-12-474056
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