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Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor
Infusions of antigen-specific T cells have yielded therapeutic responses in patients with pathogens and tumors. To broaden the clinical application of adoptive immunotherapy against malignancies, investigators have developed robust systems for the genetic modification and characterization of T cells...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2938125/ https://ncbi.nlm.nih.gov/pubmed/20439624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-043737 |
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