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Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor

Infusions of antigen-specific T cells have yielded therapeutic responses in patients with pathogens and tumors. To broaden the clinical application of adoptive immunotherapy against malignancies, investigators have developed robust systems for the genetic modification and characterization of T cells...

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Detalhes bibliográficos
Main Authors: Jena, Bipulendu, Dotti, Gianpietro, Cooper, Laurence J. N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938125/
https://ncbi.nlm.nih.gov/pubmed/20439624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-043737
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