L1 Cell Adhesion Molecule-Specific Chimeric Antigen Receptor-Redirected Human T Cells Exhibit Specific and Efficient Antitumor Activity against Human Ovarian Cancer in Mice

New therapeutic modalities are needed for ovarian cancer, the most lethal gynecologic malignancy. Recent clinical trials have demonstrated the impressive therapeutic potential of adoptive therapy using chimeric antigen receptor (CAR)-redirected T cells to target hematological cancers, and emerging s...

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Publicado en:PLoS One
Main Authors: Hong, Hao, Brown, Christine E., Ostberg, Julie R., Priceman, Saul J., Chang, Wen-Chung, Weng, Lihong, Lin, Paul, Wakabayashi, Mark T., Jensen, Michael C., Forman, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711972/
https://ncbi.nlm.nih.gov/pubmed/26761817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146885
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