L1 Cell Adhesion Molecule-Specific Chimeric Antigen Receptor-Redirected Human T Cells Exhibit Specific and Efficient Antitumor Activity against Human Ovarian Cancer in Mice

New therapeutic modalities are needed for ovarian cancer, the most lethal gynecologic malignancy. Recent clinical trials have demonstrated the impressive therapeutic potential of adoptive therapy using chimeric antigen receptor (CAR)-redirected T cells to target hematological cancers, and emerging s...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hong, Hao, Brown, Christine E., Ostberg, Julie R., Priceman, Saul J., Chang, Wen-Chung, Weng, Lihong, Lin, Paul, Wakabayashi, Mark T., Jensen, Michael C., Forman, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711972/
https://ncbi.nlm.nih.gov/pubmed/26761817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146885
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